1624792-70-6

CM-545 Chemical Structure
1624792-70-6

Chemical Structure

CM-545

  • CAS No.: 1624792-70-6
  • Formula:C23H29N5O4
  • Molecular Weight:439.51

IUPAC Name: (1r,3s)-3-(4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzyl)-N-hydroxycyclobutane-1-carboxamide

InChIKey: GTSZATFSVLYIRU-GASCZTMLSA-N

SMILES: O=C([C@H]1C[C@@H](CC2=CC=C(OCC)C(C3=NC4=C(N(C)N=C4CCC)C(N3)=O)=C2)C1)NO

Biological Activity: CM-545, the cis-isomer of CM-414 (HY-119316), is a dual inhibitor of PDE5, HDAC1, HDAC2, HDAC3, and HDAC6 with pIC50 values of 7.47, 6.65, 6.14, 6.55, and 6.84, repectively[1].

Cat. No. Product Name Purity Description Pricing
HY-119316A 		CM-545 CM-545, the cis-isomer of CM-414 (HY-119316), is a dual inhibitor of PDE5, HDAC1, HDAC2, HDAC3, and HDAC6 with pIC50 values of 7.47, 6.65, 6.14, 6.55, and 6.84, repectively.
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