2165322-95-0
Chemical Structure
USP25/28-IN-2
- CAS No.: 2165322-95-0
- Formula:C17H17BrF3NO3
- Molecular Weight:420.23
IUPAC Name: 2-((5-bromo-2-((3-(trifluoromethoxy)benzyl)oxy)benzyl)amino)ethan-1-ol
InChIKey: FUYSDKCEPZFKSP-UHFFFAOYSA-N
SMILES: FC(F)(F)OC1=CC=CC(=C1)COC2=CC=C(Br)C=C2CNCCO
Biological Activity: USP25/28-IN-2 is a selectivity dual USP25/28 inhibitor with IC50 values of 0.88 and 1.1 μM, respectively. USP25/28-IN-2 modulates USP25 and USP28 activity to affect downstream pathways, modulates c-Myc oncoprotein total levels and half-life, induces apoptosis, reduces cell viability. USP25/28-IN-2 can be used for the research of colorectal carcinoma, colorectal adenocarcinoma[1].
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USP25/28-IN-2 | USP25/28-IN-2 is a selectivity dual USP25/28 inhibitor with IC50 values of 0.88 and 1.1 μM, respectively. USP25/28-IN-2 modulates USP25 and USP28 activity to affect downstream pathways, modulates c-Myc oncoprotein total levels and half-life, induces apoptosis, reduces cell viability. USP25/28-IN-2 can be used for the research of colorectal carcinoma, colorectal adenocarcinoma. | |||||||||||||||||||||
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