331467-05-1
331467-05-1
Chemical Structure
Indirubin-3'-monoxime-5-sulphonic acid
- CAS No.: 331467-05-1
- Formula:C16H11N3O5S
- Molecular Weight:357.34
IUPAC Name: (2E,3E)-3-(hydroxyimino)-2'-oxo-[2,3'-biindolinylidene]-5'-sulfonic acid
InChIKey: VUIXUTVIIOVVHV-OIXOFKMYSA-N
SMILES: O=S(C1=CC2=C(NC(/C2=C3NC4=C(C=CC=C4)C/3=N\O)=O)C=C1)(O)=O
Biological Activity: Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of CDK1, CDK5, and GSK-3β with IC50s of 5 nM, 7 nM, and 80 nM, respectively[1].
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Indirubin-3'-monoxime-5-sulphonic acid | Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of CDK1, CDK5, and GSK-3β with IC50s of 5 nM, 7 nM, and 80 nM, respectively. | |||||||||||||||||||||
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References
