2. Cell Cycle/DNA Damage Stem Cell/Wnt PI3K/Akt/mTOR
  3. CDK GSK-3
  4. Indirubin-3'-monoxime-5-sulphonic acid

Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of CDK1, CDK5, and GSK-3β with IC50s of 5 nM, 7 nM, and 80 nM, respectively.

For research use only. We do not sell to patients.

Indirubin-3'-monoxime-5-sulphonic acid Chemical Structure

Indirubin-3'-monoxime-5-sulphonic acid Chemical Structure

CAS No. : 331467-05-1

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Indirubin-3'-monoxime-5-sulphonic acid Related Antibodies

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GSK-3 GSK-3α GSK-3β

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Description

Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of CDK1, CDK5, and GSK-3β with IC50s of 5 nM, 7 nM, and 80 nM, respectively[1].

IC50 & Target[1]

CDK1

5 nM (IC50)

CDK5

7 nM (IC50)

GSK-3β

80 nM (IC50)

Molecular Weight

357.34

Formula

C16H11N3O5S
CAS No.
SMILES

O=S(C1=CC2=C(NC(/C2=C3NC4=C(C=CC=C4)C/3=N\O)=O)C=C1)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Indirubin-3'-monoxime-5-sulphonic acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Indirubin-3'-monoxime-5-sulphonic acid331467-05-1CDKGSK-3Cyclin dependent kinaseGlycogen synthase kinase-3Glycogen synthase kinase 3Inhibitorinhibitorinhibit

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