1. Cell Cycle/DNA Damage
    Stem Cell/Wnt
    PI3K/Akt/mTOR
  2. CDK
    GSK-3
  3. Indirubin-3'-monoxime-5-sulphonic acid

Indirubin-3'-monoxime-5-sulphonic acid 

Cat. No.: HY-111931
Handling Instructions

Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of CDK1, CDK5, and GSK-3β with IC50s of 5 nM, 7 nM, and 80 nM, respectively.

For research use only. We do not sell to patients.

Indirubin-3'-monoxime-5-sulphonic acid Chemical Structure

Indirubin-3'-monoxime-5-sulphonic acid Chemical Structure

CAS No. : 331467-05-1

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Description

Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of CDK1, CDK5, and GSK-3β with IC50s of 5 nM, 7 nM, and 80 nM, respectively[1].

IC50 & Target[1]

CDK1

5 nM (IC50)

CDK5

7 nM (IC50)

GSK-3β

80 nM (IC50)

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

357.34

Formula

C₁₆H₁₁N₃O₅S

CAS No.

331467-05-1

SMILES

O=S(C1=CC2=C(NC(/C2=C3NC4=C(C=CC=C4)C/3=N\O)=O)C=C1)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Indirubin-3'-monoxime-5-sulphonic acid
Cat. No.:
HY-111931
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Indirubin-3'-monoxime-5-sulphonic acid

Cat. No.: HY-111931