CAMK1D-IN-1
Based on 1 Customer Validation
CAMK1D-IN-1 (compound I) is an inhibitor of CAMK1D, targeting cytotoxic T lymphocyte (CTL)-resistant tumor cells. CAMK1D impairs CTL-induced death receptor signaling and apoptosis by inhibiting caspases, making it a key and effective target for PD-L1-refractory tumors.
For research use only. We do not sell to patients.
- Purity: 99.06%
- CAS No.: 404828-08-6
- Formula: C18H19N5
- Molecular Weight:305.38
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 404828-08-6
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Appearance Solid
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Molecular Weight 305.38
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Formula C18H19N5
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Color White to off-white
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SMILES
CC1=CC(NC2=NC(C3=CC=CC=C3)=NC4=C2CCCC4)=NN1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (409.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2746 mL | 16.3730 mL | 32.7461 mL | 81.8652 mL |
| 5 mM | 0.6549 mL | 3.2746 mL | 6.5492 mL | 16.3730 mL | |
| 10 mM | 0.3275 mL | 1.6373 mL | 3.2746 mL | 8.1865 mL | |
| 15 mM | 0.2183 mL | 1.0915 mL | 2.1831 mL | 5.4577 mL | |
| 20 mM | 0.1637 mL | 0.8187 mL | 1.6373 mL | 4.0933 mL | |
| 25 mM | 0.1310 mL | 0.6549 mL | 1.3098 mL | 3.2746 mL | |
| 30 mM | 0.1092 mL | 0.5458 mL | 1.0915 mL | 2.7288 mL | |
| 40 mM | 0.0819 mL | 0.4093 mL | 0.8187 mL | 2.0466 mL | |
| 50 mM | 0.0655 mL | 0.3275 mL | 0.6549 mL | 1.6373 mL | |
| 60 mM | 0.0546 mL | 0.2729 mL | 0.5458 mL | 1.3644 mL | |
| 80 mM | 0.0409 mL | 0.2047 mL | 0.4093 mL | 1.0233 mL | |
| 100 mM | 0.0327 mL | 0.1637 mL | 0.3275 mL | 0.8187 mL |