404828-08-6
404828-08-6
Chemical Structure
CAMK1D-IN-1
- CAS No.: 404828-08-6
- Formula:C18H19N5
- Molecular Weight:305.38
InChIKey: FAWIBADRALTDOY-UHFFFAOYSA-N
SMILES: CC1=CC(NC2=NC(C3=CC=CC=C3)=NC4=C2CCCC4)=NN1
Biological Activity: CAMK1D-IN-1 (compound I) is an inhibitor of CAMK1D, targeting cytotoxic T lymphocyte (CTL)-resistant tumor cells. CAMK1D impairs CTL-induced death receptor signaling and apoptosis by inhibiting caspases, making it a key and effective target for PD-L1-refractory tumors[1].
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CAMK1D-IN-1 | 99.06% | CAMK1D-IN-1 (compound I) is an inhibitor of CAMK1D, targeting cytotoxic T lymphocyte (CTL)-resistant tumor cells. CAMK1D impairs CTL-induced death receptor signaling and apoptosis by inhibiting caspases, making it a key and effective target for PD-L1-refractory tumors. | ||||||||||||||||||||
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