2. Others Membrane Transporter/Ion Channel
  3. Reference Standards Potassium Channel
  4. BL-1249 (Standard)

BL-1249 (Standard) is the analytical standard of BL-1249 (HY-108596). This product is intended for research and analytical applications. BL-1249 is a nonsteroidal anti-inflammatory agent (NSAID) and a potassium channel activator. BL-1249 potently activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with EC50 values of 5.5 μM and 8.0 μM, respectively. BL-1249 extracellular application activates all TREK subfamily members but has no effect on other K2P subfamilies. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 μM) than vascular tissue (EC50 of 21.0 μM).

For research use only. We do not sell to patients.

BL-1249 (Standard)

BL-1249 (Standard) Chemical Structure

CAS No. : 18200-13-0

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Information

BL-1249 (Standard) is the analytical standard of BL-1249 (HY-108596). This product is intended for research and analytical applications. BL-1249 is a nonsteroidal anti-inflammatory agent (NSAID) and a potassium channel activator. BL-1249 potently activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with EC50 values of 5.5 μM and 8.0 μM, respectively. BL-1249 extracellular application activates all TREK subfamily members but has no effect on other K2P subfamilies. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 μM) than vascular tissue (EC50 of 21.0 μM).

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

291.35

Formula

C17H17N5
CAS No.
SMILES

C1(NC2=C3CCCCC3=CC=C2)=CC=CC=C1C4=NN=NN4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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BL-1249 (Standard) Related Classifications

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Keywords:

BL-1249 (Standard)18200-13-0Reference StandardsPotassium ChannelKcsAAnti-inflammatorynonsteroidalTREK-1TREK-2NSAIDbladdervascularhyperpolarizationC-typegateInhibitorinhibitorinhibit

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