379231-04-6
379231-04-6
Chemical Structure
Saracatinib
Synonym(s): AZD0530
- CAS No.: 379231-04-6
- Formula:C27H32ClN5O5
- Molecular Weight:542.03
IUPAC Name: N-(5-chlorobenzo[d][1,3]dioxol-4-yl)-7-(2-(4-methylpiperazin-1-yl)ethoxy)-5-((tetrahydro-2H-pyran-4-yl)oxy)quinazolin-4-amine
InChIKey: OUKYUETWWIPKQR-UHFFFAOYSA-N
SMILES: ClC1=CC=C2C(OCO2)=C1NC3=C4C(OC5CCOCC5)=CC(OCCN6CCN(C)CC6)=CC4=NC=N3
Biological Activity: Saracatinib (AZD0530) is a potent Src family inhibitor with IC50s of 2.7 to 11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr, and Blk. Saracatinib shows high selectivity over other tyrosine kinases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Saracatinib | 99.23% | Saracatinib (AZD0530) is a potent Src family inhibitor with IC50s of 2.7 to 11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr, and Blk. Saracatinib shows high selectivity over other tyrosine kinases. | ||||||||||||||||||||
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Saracatinib (Standard) | ≥98% | Saracatinib (Standard) is the analytical standard of Saracatinib. This product is intended for research and analytical applications. Saracatinib (AZD0530) is a potent Src family inhibitor with IC50s of 2.7 to 11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr, and Blk. Saracatinib shows high selectivity over other tyrosine kinases. | ||||||||||||||||||||
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Saracatinib-d3 | Saracatinib-d3 (AZD0530-d3) (ZG5129) is the deuterium-labeled analog of Saracatinib (HY-10234). Saracatinib-d3 is an inhibitor of the Src kinase, which can inhibit severe sepsis caused by bacterial or various microbial infections. | |||||||||||||||||||||
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References
