43218-56-0
43218-56-0
Chemical Structure
Midodrine hydrochloride
Synonym(s): (±)-Midodrine hydrochloride
- CAS No.: 43218-56-0
- Formula:C12H19ClN2O4
- Molecular Weight:290.74
IUPAC Name: 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)acetamide hydrochloride
InChIKey: MGCQZNBCJBRZDT-UHFFFAOYSA-N
SMILES: O=C(NCC(C1=CC(OC)=CC=C1OC)O)CN.[H]Cl
Biological Activity: Midodrine hydrochloride ((±)-Midodrine hydrochloride) is a selective and orally active adrenergic α1-receptor agonist. Midodrine hydrochloride can strengthen vascular contraction. Midodrine hydrochloride can be used for the researches of cardiovascular disease, such as orthostatic hypotension[1][2][3].
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Midodrine hydrochloride | 99.9% | Midodrine hydrochloride ((±)-Midodrine hydrochloride) is a selective and orally active adrenergic α1-receptor agonist. Midodrine hydrochloride can strengthen vascular contraction. Midodrine hydrochloride can be used for the researches of cardiovascular disease, such as orthostatic hypotension. | ||||||||||||||||||||
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Midodrine-d6 hydrochloride | 99.44% | Midodrine-d6 (hydrochloride) is a selective and orally active adrenergic α1-receptor agonist. Midodrine-d6 (hydrochloride) can strengthen vascular contraction. Midodrine-d6 (hydrochloride) can be used for the researches of cardiovascular disease, such as orthostatic hypotension. | ||||||||||||||||||||
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References
- [1]. Criscuoli M, et al. Catecholamines released from the adrenal medulla exert a compensatory, protective effect at beta 2-adrenoceptors against Paf-induced death in mice. Br J Pharmacol. 1988 Jan;93(1):132-8. [Content Brief]
- [2]. Inchan A, et al. Anti-hypotensive effect of "Yahom Navakot" in rats with orthostatic hypotension. J Tradit Complement Med. 2021 Aug 3;12(2):180-189. [Content Brief]
- [3]. Lee YJ, et al. Stimulation of Alpha1-Adrenergic Receptor Ameliorates Cellular Functions of Multiorgans beyond Vasomotion through PPARδ. PPAR Res. 2020 Feb 1;2020:3785137. [Content Brief]
