612847-09-3
612847-09-3
Chemical Structure
AKT inhibitor VIII
Synonym(s): AKTi-1/2
- CAS No.: 612847-09-3
- Formula:C34H29N7O
- Molecular Weight:551.64
IUPAC Name: 1-(1-(4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl)piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
InChIKey: ABHXNLSQDUAVFP-UHFFFAOYSA-N
SMILES: O=C1NC2=CC=CC=C2N1C3CCN(CC3)CC4=CC=C(C=C4)C5=NC6=CC7=C(C=C6N=C5C8=CC=CC=C8)N=CN7
Biological Activity: AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively.
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AKT inhibitor VIII | 98.36% | AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively. | ||||||||||||||||||||
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AKT inhibitor VIII (Standard) | ≥98% | AKT inhibitor VIII (Standard) is the analytical standard of AKT inhibitor VIII (HY-10355). This product is intended for research and analytical applications. AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively. | ||||||||||||||||||||
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