2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. RAR/RXR
  4. CD3254

CD3254 a potent and selective retinoid-X-receptor (RXR) agonist.

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CD3254

CD3254 화학구조

CAS No. : 196961-43-0

사이즈 가격 재고 수량
무료 샘플 (0.1 - 0.2 mg)   지금 신청하기  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg   견적 받기  
200 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 3 publication(s) in Google Scholar

Other Forms of CD3254:

CD3254 Related Antibodies

Top Publications Citing Use of Products

View All RAR/RXR Isoform Specific Products:

View All Isoforms
RXRα RXRβ RXRγ

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

CD3254 a potent and selective retinoid-X-receptor (RXR) agonist[1].

In Vitro

CD3254 induces similar phenotypes of malformations after 5 days exposure at low concentration (20 μg/L) to those after the 1st d exposure at high concentrations (50 and 100 μg/L)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CD3254 Related Antibodies

Cell Viability Assay[1]

Cell Line: zebrafish (Danio rerio) embryos
Concentration: 10, 20, 50, 100 μg/L
Incubation Time:
Result: The percent of survival decreased by 19.1 % in 100 μg/L CD3254-treated group after the 1st day exposure. The embryos did not hatch in groups exposed to 100 μg/L CD3254 for 5 days or to 1 mg/L CD3254 for the 1st day.
분자량

364.48

화학식

C24H28O3
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

CC1(C2=CC(C3=CC(/C=C\C(O)=O)=CC=C3O)=C(C)C=C2C(C)(C)CC1)C
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
용액&용해도
In Vitro: 

DMSO : 125 mg/mL (342.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7436 mL 13.7182 mL 27.4363 mL
5 mM 0.5487 mL 2.7436 mL 5.4873 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7436 mL 13.7182 mL 27.4363 mL 68.5909 mL
5 mM 0.5487 mL 2.7436 mL 5.4873 mL 13.7182 mL
10 mM 0.2744 mL 1.3718 mL 2.7436 mL 6.8591 mL
15 mM 0.1829 mL 0.9145 mL 1.8291 mL 4.5727 mL
20 mM 0.1372 mL 0.6859 mL 1.3718 mL 3.4295 mL
25 mM 0.1097 mL 0.5487 mL 1.0975 mL 2.7436 mL
30 mM 0.0915 mL 0.4573 mL 0.9145 mL 2.2864 mL
40 mM 0.0686 mL 0.3430 mL 0.6859 mL 1.7148 mL
50 mM 0.0549 mL 0.2744 mL 0.5487 mL 1.3718 mL
60 mM 0.0457 mL 0.2286 mL 0.4573 mL 1.1432 mL
80 mM 0.0343 mL 0.1715 mL 0.3430 mL 0.8574 mL
100 mM 0.0274 mL 0.1372 mL 0.2744 mL 0.6859 mL
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CD3254 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CD3254196961-43-0CD 3254CD-3254RAR/RXRRetinoic acid receptorsRetinoid X receptorsRXRzebrafishembryos,Inhibitorinhibitorinhibit

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Inquiry Information

상품명:
CD3254
Cat. No.:
HY-107399
수량:
MCE Japan Authorized Agent:

고객리뷰

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