Cevipabulin fumarate dihydrate
Based on 2 publication(s) in Google Scholar
Cevipabulin (TTI-237) fumarate dihydrate) is an oral, microtubule-active, antitumor compound and inhibits the binding of [3H]NSC 49842 to tubulin, with an IC50 of 18-40 nM for cytotoxicity in human tumor cell line.
For research use only. We do not sell to patients.
- CAS No.: 849550-69-2
- Formula: C22H26ClF5N6O7
- Molecular Weight:616.92
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Cevipabulin fumarate dihydrate
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Biological Activity
Chemical Information
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CAS No. 849550-69-2
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Molecular Weight 616.92
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Formula C22H26ClF5N6O7
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SMILES
C[C@@]([H])(C(F)(F)F)NC1=C(C2=C(F)C=C(OCCCNC)C=C2F)C(Cl)=NC3=NC=NN13.O=C(O)/C=C/C(O)=O.O.O
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Synonyms
TTI-237 fumarate dihydrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Biochem Biophys Res Commun
2019 Aug 27;516(3):760-764. PMID: 31253401
Purity & Documentation
References
[1]. Beyer CF, et al. TTI-237: a novel microtubule-active compound with in vivo antitumor activity. Cancer Res. 2008 Apr 1;68(7):2292-300. [Content Brief]
[2]. Beyer CF, et al. The microtubule-active antitumor compound TTI-237 has both DB01229-like and Leurocristine-like properties. Cancer Chemother Pharmacol. 2009 Sep;64(4):681-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cevipabulin fumarate dihydrate Related Classifications
HY-14949D Related Classifications
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