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Art. -Nr.: HY-N21534

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7α-Hydroxydehydroabietic acid

7α-Hydroxydehydroabietic acid is a diterpene acid that can be found in the leaves of Larix kaempferi.

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CAS. Nr.: 76235-98-8
Formel: C₂₀H₂₈O₃
Molecular Weight:316.44

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

7α-Hydroxydehydroabietic acid Chemical Structure

CAS. Nr.: 76235-98-8

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

7α-Hydroxydehydroabietic acid is a diterpene acid that can be found in the leaves of Larix kaempferi^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	10 μM Compound: 21	Cytotoxicity in human A549 cells by SRB assay Cytotoxicity in human A549 cells by SRB assay	[PMID: 26812172]
HCT-116	IC₅₀	10 μM Compound: 21	Cytotoxicity in human HCT116 cells by SRB assay Cytotoxicity in human HCT116 cells by SRB assay	[PMID: 26812172]
HEK293	IC₅₀	100 μg/mL Compound: 42	Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells	[PMID: 20022253]
LoVo	IC₅₀	25 μg/mL Compound: 42	Antiproliferative activity against human LoVo cells Antiproliferative activity against human LoVo cells	[PMID: 20022253]
QGY-7703	IC₅₀	25 μg/mL Compound: 42	Antiproliferative activity against human QGY7703 cells Antiproliferative activity against human QGY7703 cells	[PMID: 20022253]
RAW264.7	IC₅₀	100 μg/mL Compound: 42	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release	[PMID: 20022253]
SK-MEL-2	IC₅₀	10 μM Compound: 21	Cytotoxicity in human SK-MEL-2 cells by SRB assay Cytotoxicity in human SK-MEL-2 cells by SRB assay	[PMID: 26812172]
SK-OV-3	IC₅₀	10 μM Compound: 21	Cytotoxicity in human SKOV3 cells by SRB assay Cytotoxicity in human SKOV3 cells by SRB assay	[PMID: 26812172]

In Vitro

7α-Hydroxydehydroabietic acid (isolated as methyl 7α-hydroxydehydroabietate) is identified from Larix kaempferi leaves based on matching physical and spectral data with published references, with a molecular ion peak at m/z 330 [M]⁺^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 76235-98-8
Molecular Weight 316.44
Formel C₂₀H₂₈O₃
SMILES

C[C@@]12[C@]([C@@](C(O)=O)(C)CCC1)(C[C@@H](O)C=3C2=CC=C(C(C)C)C3)[H]
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Tanaka R, et al. Abietane diterpene acids and other constituents from the leaves of Larix kaempferi. Phytochemistry. 1997;46(6):1051–1057.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

7α-Hydroxydehydroabietic acid

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7α-Hydroxydehydroabietic acid

Biologische Aktivität

Beschreibung

Cellular Effect

In Vitro

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

7α-Hydroxydehydroabietic acid Related Classifications

HY-N21534 Related Classifications

Bioz

Keywords

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