(+)-Tuberine
(+)-Tuberine is an alkaloid found in Haplophyllum tuberculatum, with antibacterial and antifungal activities. (+)-Tuberine can be used in studies on antimicrobial natural products and microbial growth inhibition.
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- CAS. Nr.: 97400-75-4
- Formel: C27H35NO6
- Molecular Weight:469.58
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
(+)-Tuberine (0.1, 1 μg/mL; 37°C; 24-48 h) inhibits the growth of S. aureus, B. subtilis, and E. coli in the disk diffusion assay; at 1 μg/mL, it produces inhibition zones of 10-15 mm against S. aureus and B. subtilis, while generating inhibition zones of 2-5 mm against E. coli[1].
(+)-Tuberine (1 μg/mL; 37°C; 24 h) significantly inhibits the growth of B. subtilis and S. aureus in the liquid culture plate count assay, with both dropping to below 106 CFU/mL at 24 h, while it only exerts weak inhibitory effects on E. coli[1].
(+)-Tuberine (0.1, 1 μg/mL; 37°C; 12 h) inhibits B. subtilis, E. coli, and S. aureus in turbidity assays, with inhibition rates of 84%, 48%, and 85% at 0.1 μg/mL, and 86%, 50%, and 94% at 1 μg/mL[1].
(+)-Tuberine (0.1, 1 μg/mL; 37°C; 24-48 h) inhibits the growth of S. cerevisiae in the disc diffusion assay, producing an inhibition zone of 6-10 mm at 1 μg/mL[1].
(+)-Tuberine (1 μg/mL; 37°C; 24 h) inhibits the growth of S. cerevisiae in liquid culture plate counting assays[1].
(+)-Tuberine (0.1, 1 μg/mL; 37°C; 12 h) exhibits inhibition rates of 84% and 91% against S. cerevisiae in turbidity assays[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 97400-75-4
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Molecular Weight 469.58
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Formel C27H35NO6
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SMILES
[C@](OC(C)=O)(C)(C)[C@H]1O[C@@]([C@@H](COC2=CC=C(CCNC(=O)C3=CC=CC=C3)C=C2)O)(C)CC1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)