Azo-mustard
Azo-mustard is a nitrogen mustard derivative with mutagenic effects in Drosophila melanogaster males.
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- CAS. Nr.: 4213-40-5
- Formel: C18H19Cl2N3O2
- Molecular Weight:380.27
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 4213-40-5
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Molecular Weight 380.27
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Formel C18H19Cl2N3O2
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SMILES
O=C(C1=C(/N=N/C2=CC=C(N(CCCl)CCCl)C=C2C)C=CC=C1)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Genotoxicity/Mutagenicity Study
The bacterial reverse mutation assay detects point mutations that restore amino-acid prototrophy in auxotrophic Salmonella typhimurium or Escherichia coli tester strains; after exposure to a test article, mutagenic activity is read out as an increased number of revertant colonies on minimal agar compared with the vehicle control. The assay uses tester strains with different mutation targets so that base-substitution and frameshift mutagens can be detected, and testing is performed with and without exogenous mammalian metabolic activation because some chemicals require biotransformation to become mutagenic.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)