Dehydrodeguelin
Dehydrodeguelin (6a,12a-Dehydrodeguelin) is a nature product that could be isolated from the leaves of Amorpha fruticosa L.
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- CAS. Nr.: 3466-23-7
- Formel: C23H20O6
- Molecular Weight:392.40
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Astrocyte | IC50 |
>80 μM
Compound: 2
|
Growth inhibition of Nf1 defective and Trp53 defective mouse primary astrocytes after 2 hrs by XTT assay
Growth inhibition of Nf1 defective and Trp53 defective mouse primary astrocytes after 2 hrs by XTT assay
|
[PMID: 26467198] |
| B16 | IC50 |
0.56 μM
Compound: 8
|
Cytotoxicity against mouse B16 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse B16 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 28665590] |
| HepG2 | IC50 |
0.56 μM
Compound: 8
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 28665590] |
| L5178Y | IC50 |
10.2 μM
Compound: 28
|
Cytotoxicity against mouse L5178Y cells by MTT assay
Cytotoxicity against mouse L5178Y cells by MTT assay
|
[PMID: 28075580] |
| Lewis lung carcinoma cell line | IC50 |
0.56 μM
Compound: 8
|
Cytotoxicity against mouse LL/2 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse LL/2 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 28665590] |
| NCI-H1299 | IC50 |
>500 μM
Compound: 12
|
Cytotoxicity against human H1299 cells after 3 days by MTS assay
Cytotoxicity against human H1299 cells after 3 days by MTS assay
|
[PMID: 23186287] |
Chemical Information
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CAS. Nr. 3466-23-7
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Molecular Weight 392.40
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Formel C23H20O6
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SMILES
O=C1C2=C(COC3=CC(OC)=C(OC)C=C32)OC4=C5C=CC(C)(C)OC5=CC=C14
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Synonyms
6a,12a-Dehydrodeguelin
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)