Usp47 - ubiquitin specific peptidase 47 Gene

Also Known as 4930502N04Rik; A630020C16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74996

Summary

Predicted to enable WD40-repeat domain binding activity; cysteine-type endopeptidase activity; and thiol-dependent Deubiquitinase. Involved in cellular response to UV. Acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Predicted to be located in cytoplasm. Predicted to be part of SCF ubiquitin Ligase complex. Predicted to be active in cytosol and nucleus. Orthologous to human USP47 (ubiquitin specific peptidase 47). [provided by Alliance of Genome Resources, Apr 2022]

Usp47 Products (4)

mRNA Protein Name
NM_001357952.2 NP_001344881.1 ubiquitin carboxyl-terminal hydrolase 47 isoform 3
NM_001403494.1 NP_001390423.1 ubiquitin carboxyl-terminal hydrolase 47 isoform 4
NM_133758.4 NP_598519.2 ubiquitin carboxyl-terminal hydrolase 47 isoform 2
NM_177249.4 NP_796223.2 ubiquitin carboxyl-terminal hydrolase 47 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Verweise Source
involved in cellular response to UV IMP
IMP: Inferred from mutant phenotype
19966869 MGI
acts upstream of intrinsic apoptotic signaling pathway in response to DNA damage IMP
IMP: Inferred from mutant phenotype
19966869 MGI
acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage IMP
IMP: Inferred from mutant phenotype
19966869 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 47

  • deubiquitinating enzyme 47

  • ubiquitin specific protease 47

  • ubiquitin thioesterase 47

  • ubiquitin thiolesterase 47

  • ubiquitin-specific-processing protease 47

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-13865 P 22077 Inhibitor 98.42% Unkown
HY-112937 GNE-6640 Inhibitor 99.91% Unkown
HY-134817 USP7-IN-8 Inhibitor 99.04% Unkown
HY-13487 USP7/USP47 inhibitor Inhibitor 98.58% Unkown
HY-RS15558 USP47 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174301 USP7-IN-18 / Unkown
HY-111166 USP7/USP47 inhibitor 1 Inhibitor / Unkown
HY-RS17715 Usp47 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24180 Usp47 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp47 NCBI NCBI:55031