GW 275175X
GW 275175X is an inhibitor of the terminase complex involved in cleavage and packaging of the unit length DNA into the capsids. GW 275175X exhibits long plasma half-life. GW 275175X is a BDCRB derivative. GW 275175X exhibits anti-HCMV activity through inhibiting maturation of viral DNA.
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- CAS. Nr.: 217950-62-4
- Formel: C12H11BrCl2N2O4
- Molecular Weight:398.04
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 217950-62-4
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Molecular Weight 398.04
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Formel C12H11BrCl2N2O4
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SMILES
O[C@H]1[C@H](N2C3=CC(Cl)=C(Cl)C=C3N=C2Br)OC[C@@H](O)[C@H]1O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Emery, V. C., & Hassan-Walker, A. F. (2002). Focus on new drugs in development against human cytomegalovirus. Drugs, 62(13), 1853-1858. [Content Brief]
[2]. Williams, S. L., et al., (2003). In vitro activities of benzimidazole D- and L-ribonucleosides against herpesviruses. Antimicrobial agents and chemotherapy, 47(7), 2186-2192. [Content Brief]
[3]. McGregor, A., & Choi, K. Y. (2011). Cytomegalovirus antivirals and development of improved animal models. Expert opinion on drug metabolism & toxicology, 7(10), 1245-1265. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
GW 275175X Related Classifications
HY-117137 Related Classifications
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