Isatoic anhydride

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Isatoic anhydride is a single-adduct forming reagent and a monofunctional SHAPE reagent. Isatoic anhydride reacts with the 2'-hydroxyl group of RNA nucleotides via a single reactive group to form a single adduct, without forming cross-links between nucleotides. In SHAPE-JuMP experiments, Isatoic anhydride serves as a control reagent for single-adduct formation, which is used to distinguish true cross-links from single-adduct formation.

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  • Reinheit: 99.26%
  • CAS. Nr.: 118-48-9
  • Formel: C8H5NO3
  • Molecular Weight:163.13
  • Speicherung:

    Store at room temperature 3 years.

    In solvent   -80°C, 2 years , -20°C, 1 year
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