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Art. -Nr.: HY-187569

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(Rac)-3-OH-Simvastatin

(Rac)-3-OH-Simvastatin is a metabolite of Simvastatin (HY-17502). Simvastatin is an orally active competitive inhibitor of HMG-CoA reductase (HMGCR) with a K_i of 0.2 nM.

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CAS. Nr.: 134523-09-4
Formel: C₂₅H₃₈O₆
Molecular Weight:434.57

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

(Rac)-3-OH-Simvastatin Chemical Structure

CAS. Nr.: 134523-09-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

(Rac)-3-OH-Simvastatin is a metabolite of Simvastatin (HY-17502). Simvastatin is an orally active competitive inhibitor of HMG-CoA reductase (HMGCR) with a K_i of 0.2 nM^[1].

Chemical Information

CAS. Nr. 134523-09-4
Molecular Weight 434.57
Formel C₂₅H₃₈O₆
SMILES

O=C1OC(CC(C1)O)CCC2C(C)C=CC3=CC(C)(CC(C32)OC(C(C)(CC)C)=O)O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Vickers S, et al. In vitro and in vivo biotransformation of simvastatin, an inhibitor of HMG CoA reductase. Drug Metab Dispos. 1990 Jul-Aug;18(4):476-83. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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