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Tominersen sodium

(Synonyms: RG6042 sodium; IONIS-HTTRx sodium)
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Tominersen sodium is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen improves survival and reduces brain atrophy in mice. Tominersen sodium can be used for the research of Huntington’s disease (HD).

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  • Reinheit: 97.36%
  • Formel: C230H299N74Na20O122P19S13
  • Molecular Weight:7078 (free acid)
  • Speicherung:

    -20°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Tominersen sodium Chemical Structure
    Tominersen sodium Chemical Structure
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Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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  • Tominersen sodium Chemical Structure
    Tominersen sodium Chemical Structure DNA, d([2'-O-(2-methoxyethyl)]m5rC-sp-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-[2'-O-(2-methoxyethyl)]rG-sp-T-sp-A-sp-A-sp-m5C-sp-A-sp-T-sp-T-sp-G-spA-sp-m5C-sp-[2'-O-(2-methoxyethyl)]rA-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]m5rC), sodium salt
    1/16
  • DNA, d([2'-O-(2-methoxyethyl)]m5rC-sp-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-[2'-O-(2-methoxyethyl)]rG-sp-T-sp-A-sp-A-sp-m5C-sp-A-sp-T-sp-T-sp-G-spA-sp-m5C-sp-[2'-O-(2-methoxyethyl)]rA-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]m5rC), sodium salt