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Art. -Nr.: HY-111286

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WNK-IN-2

WNK-IN-2 is an ATP-competitive WNK kinase inhibitor with low kinase selectivity.

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CAS. Nr.: 853298-47-2
Formel: C₂₇H₃₂F₃N₇O₂
Molecular Weight:543.60

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

WNK-IN-2 Chemical Structure

CAS. Nr.: 853298-47-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

WNK-IN-2 is an ATP-competitive WNK kinase inhibitor with low kinase selectivity^[1].

In Vitro

WNK-IN-2 (compound 3) exhibits low selectivity for WNK1 and shows stronger inhibitory activity against multiple off-target kinases in a screening panel containing 31 kinases^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS. Nr. 853298-47-2
Molecular Weight 543.60
Formel C₂₇H₃₂F₃N₇O₂
SMILES

O=C(NC1=CC=C(OC2=NC(=NC=C2)NC)C=C1)NC3=CC=C(C(=C3)C(F)(F)F)CN4CCN(CC4)C(C)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Yamada K, et al. Discovery and Characterization of Allosteric WNK Kinase Inhibitors. ACS Chem Biol. 2016;11(12):3338-3346. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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