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Cat. No.: HY-106352

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BMS 605339

BMS 605339 is a linear tetra-peptide α-ketoamide inhibitor of HCV NS3 protease. BMS 605339 can be used in research related to hepatitis C (HCV infection).

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 630417-82-2
Formule: C₃₅H₄₇N₅O₉S
Masse moléculaire:713.84

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

BMS 605339 Chemical Structure

CAS No.: 630417-82-2

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Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

BMS 605339 is a linear tetra-peptide α-ketoamide inhibitor of HCV NS3 protease. BMS 605339 can be used in research related to hepatitis C (HCV infection)^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
Huh-7	CC₅₀	>100 μM Compound: 35, BMS-605339	Cytotoxicity against human HuH7 cells Cytotoxicity against human HuH7 cells	[PMID: 24555570]
Huh-7	EC₅₀	12 nM Compound: 1; BMS-605339	Antiviral activity against HCV genotype 1b Con1 expressing NS3 protease infected in human Huh7.5 cells assessed as reduction in viral RNA replication by luciferase reporter gene assay Antiviral activity against HCV genotype 1b Con1 expressing NS3 protease infected in human Huh7.5 cells assessed as reduction in viral RNA replication by luciferase reporter gene assay	[PMID: 27564532]

Chemical Information

CAS No. 630417-82-2
Masse moléculaire 713.84
Formule C₃₅H₄₇N₅O₉S
SMILES

O=C([C@H]1N(C[C@H](OC2=NC=CC3=C2C=CC(OC)=C3)C1)C([C@H](C(C)(C)C)NC(OC(C)(C)C)=O)=O)N[C@]4([C@H](C=C)C4)C(NS(=O)(C5CC5)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wang H, et al. Computational study on the drug resistance mechanism of HCV NS3 protease to BMS-605339. Biotechnol Appl Biochem. 2017 Mar;64(2):153-164. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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