DMX-5804 (Standard)

DMX-5804 (Standard) is the analytical standard of DMX-5804 (HY-111754). This product is intended for research and analytical applications. DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96). DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice.

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  • CAS No.: 2306178-56-1
  • Formule: C21H19N3O3
  • Masse moléculaire:361.39
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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