PknB-IN-2
PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC50 of 12.1 μM.
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- CAS No.: 500015-22-5
- Formule: C28H32N2O4
- Masse moléculaire:460.56
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
IC50: 12.1 μM (PknB)[1]
In Vitro
PknB-IN-2 (Compound 10) shows encouraging growth inhibition activity toward the M. tuberculosis H37Rv strain, with a MIC value of 6.2 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 500015-22-5
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Masse moléculaire 460.56
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Formule C28H32N2O4
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SMILES
OCC(NCC(O)CN1C(C2=CC=CC=C2)=C(C3=CC=CC=C3)C4=C1C=CC(C)=C4)(CO)CO
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PknB-IN-2 Related Classifications
HY-151206 Related Classifications
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