- Click Chemistry
- DBCO
DBCO
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DBCO (328)
- Formula: C21H20N2O3
- Molecular Weight: 348.40
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- Formula: C36H43N3O11
- Molecular Weight: 693.74
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- Formula: C58H70N4O13
- Molecular Weight: 1031.20
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- Formula: C44H65N3O13
- Molecular Weight: 844.00
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- Formula: C38H52N2O12
- Molecular Weight: 728.83
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- Formula: C54H74N6O16S
- Molecular Weight: 1095.26
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formula: C25H29N3O4
- Molecular Weight: 435.52
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- Formula: C34H39N3O10
- Molecular Weight: 649.69
DBCO-NHCO-PEG4-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-NHCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formula: C32H40N2O9
- Molecular Weight: 596.67
DBCO-Amide-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-Amide-PEG5-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-NHCO-PEG4-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formula: C69H94N12O16
- Molecular Weight: 1347.56
DBCO-(PEG2-Val-Cit-PAB)2 is a dual cleavable ADC linker for antibody-drug conjugates (ADCs). DBCO-(PEG2-Val-Cit-PAB)2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-(PEG2-Val-Cit-PAB)2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formula: C54H61N4O7P
- Molecular Weight: 909.06
DBCO Phosphoramidite is a phosphoramidite reagent containing a dibenzocyclooctyne (DBCO) moiety, which can introduce a strain-promoted alkyne group for copper-free click chemistry into DNA strands during solid-phase oligonucleotide synthesis. DBCO Phosphoramidite is applicable to studies related to oligonucleotide modification, copper-free click conjugation, and functionalized DNA nanomaterials.
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- Formula: C69H80N7O11P
- Molecular Weight: 1214.39
DBCO-dT Phosphoramidite is a coupling agent. DBCO-dT Phosphoramidite serves as a nucleoside-based phosphoramidite building block with a dibenzocyclooctyne (DBCO) functionality. DBCO-dT Phosphoramidite undergoes covalent coupling with azide-labeled biomolecules via metal-free click chemistry. DBCO-dT Phosphoramidite enables the introduction of click chemistry reactive groups into flexible nanoarray linkers and internal sites of oligonucleotide chains during solid-phase synthesis.
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- Formula: C38H53N4O7P
- Molecular Weight: 708.84
5'-DBCO-TEG Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- Molecular Weight: 1000 (Average)
DBCO-PEG1000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material.
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- Formula: C53H57KN4O8S2
- Molecular Weight: 981.27
Sulfo-Cyanine5 DBCO is a near-infrared red (NIR) fluorescent dye. Sulfo-Cyanine5 DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em =646/670 nm).
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- Formula: C24H26N2O4
- Molecular Weight: 406.47
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- Formula: C36H38N6O6
- Molecular Weight: 650.72
Methyltetrazine-PEG4-DBCO is a PEG linker with a terminal TCO reactive reagent and a DBCO group. DBCO is commonly used for copper-free Click Chemistry reactions. Methyltetrazine can be used to convert azido-containing peptides or proteins into tetrazine-modified peptides or protein without catalyst or axillary reagents.
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- Formula: C32H30N6O4
- Molecular Weight: 562.62
Methyltetrazine-PEG2-DBCO is a TCO reactive reagent with a DBCO group and water-soluble PEG spacer. This reagent can be used to convert azido-containing peptides or proteins into tetrazine-modified peptides or protein without catalyst or axillary reagents. DBCO is commonly used for copper-free Click Chemistry reactions.
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- Formula: C41H56N2O14
- Molecular Weight: 800.89
DBCO-N-bis(PEG4-acid) is a branched click chemistry reagent. The DBCO group enables copper-free Click Chemistry reactions. carboxylic acid groups allows for reactions with primary amine groups using activators such as EDC or HATU to form a stable amide bond.
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