DBCO Phosphoramidite
Based on 1 Customer Validation
DBCO Phosphoramidite is a phosphoramidite reagent containing a dibenzocyclooctyne (DBCO) moiety, which can introduce a strain-promoted alkyne group for copper-free click chemistry into DNA strands during solid-phase oligonucleotide synthesis. DBCO Phosphoramidite is applicable to studies related to oligonucleotide modification, copper-free click conjugation, and functionalized DNA nanomaterials.
For research use only. We do not sell to patients.
- Purity : 95.0%
- Formula: C54H61N4O7P
- Molecular Weight:909.06
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Description
In Vitro
Chemical Information
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Appearance Solid
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Molecular Weight 909.06
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Formula C54H61N4O7P
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Color White to off-white
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SMILES
O=C(CCCCC(N1C(C=CC=C2)=C2C#CC(C=CC=C3)=C3C1)=O)NC(COC(C4=CC=C(C=C4)OC)(C5=CC=CC=C5)C6=CC=C(C=C6)OC)COP(N(C(C)C)C(C)C)OCCC#N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (110.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1000 mL | 5.5002 mL | 11.0004 mL | 27.5009 mL |
| 5 mM | 0.2200 mL | 1.1000 mL | 2.2001 mL | 5.5002 mL | |
| 10 mM | 0.1100 mL | 0.5500 mL | 1.1000 mL | 2.7501 mL | |
| 15 mM | 0.0733 mL | 0.3667 mL | 0.7334 mL | 1.8334 mL | |
| 20 mM | 0.0550 mL | 0.2750 mL | 0.5500 mL | 1.3750 mL | |
| 25 mM | 0.0440 mL | 0.2200 mL | 0.4400 mL | 1.1000 mL | |
| 30 mM | 0.0367 mL | 0.1833 mL | 0.3667 mL | 0.9167 mL | |
| 40 mM | 0.0275 mL | 0.1375 mL | 0.2750 mL | 0.6875 mL | |
| 50 mM | 0.0220 mL | 0.1100 mL | 0.2200 mL | 0.5500 mL | |
| 60 mM | 0.0183 mL | 0.0917 mL | 0.1833 mL | 0.4583 mL | |
| 80 mM | 0.0138 mL | 0.0688 mL | 0.1375 mL | 0.3438 mL | |
| 100 mM | 0.0110 mL | 0.0550 mL | 0.1100 mL | 0.2750 mL |