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Cat. No.: HY-179099

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WDR5 probe 1

Multi-target kinase-IN-8 (compound 16) is an efficient and highly selective WDR5 chemical probe. Multi-target kinase-IN-8 is a pharmaceutical intermediate. Multi-target kinase-IN-8 can be used for cancer research.

For research use only. We do not sell to patients.

Formula: C₂₉H₂₇F₃N₆O₂S
Molecular Weight:580.62

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

WDR5 probe 1 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

Molecular Weight 580.62
Formula C₂₉H₂₇F₃N₆O₂S
SMILES

C#CC[C@@H](C(N1CCC2=C(C1)C=CS2)=O)NC(C3=CC(CN4C=CN=C4)=CC(C5=CN(N=C5C(F)(F)F)CC)=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hoffmann L, et al. Discovery of an exquisitely selective WDR5 chemical probe accelerated by a high-quality DEL–ML Hit[J]. RSC chemical biology, 2025, 6(10): 1585-1594. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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