Desamino lenalidomide-C2-COOH
Based on 1 Customer Validation
Desamino lenalidomide-C2-COOH is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
For research use only. We do not sell to patients.
- Purity: 98.29%
- CAS No.: 2703770-71-0
- Formula: C16H16N2O5
- Molecular Weight:316.31
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
More
Biological Activity
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2703770-71-0
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Appearance Solid
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Molecular Weight 316.31
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Formula C16H16N2O5
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Color White to off-white
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SMILES
O=C(O)CCC1=CC=C2C(=C1)C(=O)N(C2)C3C(=O)NC(=O)CC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 83.33 mg/mL (263.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (242 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1615 mL | 15.8073 mL | 31.6146 mL | 79.0364 mL |
| 5 mM | 0.6323 mL | 3.1615 mL | 6.3229 mL | 15.8073 mL | |
| 10 mM | 0.3161 mL | 1.5807 mL | 3.1615 mL | 7.9036 mL | |
| 15 mM | 0.2108 mL | 1.0538 mL | 2.1076 mL | 5.2691 mL | |
| 20 mM | 0.1581 mL | 0.7904 mL | 1.5807 mL | 3.9518 mL | |
| 25 mM | 0.1265 mL | 0.6323 mL | 1.2646 mL | 3.1615 mL | |
| 30 mM | 0.1054 mL | 0.5269 mL | 1.0538 mL | 2.6345 mL | |
| 40 mM | 0.0790 mL | 0.3952 mL | 0.7904 mL | 1.9759 mL | |
| 50 mM | 0.0632 mL | 0.3161 mL | 0.6323 mL | 1.5807 mL | |
| 60 mM | 0.0527 mL | 0.2635 mL | 0.5269 mL | 1.3173 mL | |
| 80 mM | 0.0395 mL | 0.1976 mL | 0.3952 mL | 0.9880 mL | |
| 100 mM | 0.0316 mL | 0.1581 mL | 0.3161 mL | 0.7904 mL |
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