Diethylstilbestrol-d₈

Name: Diethylstilbestrol-d 8
Brand: MedChemExpress
SKU: HY-14598S
Rating: 4.5 (0 reviews)

製品番号: HY-14598S 純度: 99%: Data Sheet SDS COA 取扱説明書
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Diethylstilbestrol-d₈ is the deuterium labeled Diethylstilbestrol. Diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Diethylstilbestrol-d₈ 構造式

CAS 番号 : 91318-10-4

容量	価格（税別）	在庫状況	数量
1 mg	$83	在庫あり	Estimated Time of Arrival: December 31
5 mg	$250	在庫あり	Estimated Time of Arrival: December 31
10 mg	$400	在庫あり	Estimated Time of Arrival: December 31
25 mg	$831	お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of Diethylstilbestrol-d₈:

Diethylstilbestrol 在庫あり

Estrogen Receptor/ERR アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Diethylstilbestrol-d₈ is the deuterium labeled Diethylstilbestrol. Diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders^[1]^[2].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

276.40

分子式

C₁₈H₁₂D₈O₂

CAS 番号

91318-10-4

Unlabeled CAS

56-53-1

Appearance

Solid

Color

White to off-white

SMILES

CC([2H])([2H])/C(C1=CC([2H])=C(C([2H])=C1)O)=C(C2=CC([2H])=C(C([2H])=C2)O)/C([2H])([2H])C

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 50 mg/mL (180.90 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6179 mL	18.0897 mL	36.1795 mL
5 mM	0.7236 mL	3.6179 mL	7.2359 mL
10 mM	0.3618 mL	1.8090 mL	3.6179 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.74%

Select Batch:

データシート (275 KB) SDS (761 KB)

COA (253 KB) HNMR (387 KB) RP-HPLC (656 KB) Elemental Analysis Report (111 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Troisi, R., et al., Medical conditions among adult offspring prenatally exposed to diethylstilbestrol. Epidemiology, 2013. 24(3): p. 430-8. [Content Brief]

[3]. Kebir, O. and M.O. Krebs, Diethylstilbestrol and risk of psychiatric disorders: a critical review and new insights. World J Biol Psychiatry, 2012. 13(2): p. 84-95. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.6179 mL	18.0897 mL	36.1795 mL	90.4486 mL
	5 mM	0.7236 mL	3.6179 mL	7.2359 mL	18.0897 mL
	10 mM	0.3618 mL	1.8090 mL	3.6179 mL	9.0449 mL
	15 mM	0.2412 mL	1.2060 mL	2.4120 mL	6.0299 mL
	20 mM	0.1809 mL	0.9045 mL	1.8090 mL	4.5224 mL
	25 mM	0.1447 mL	0.7236 mL	1.4472 mL	3.6179 mL
	30 mM	0.1206 mL	0.6030 mL	1.2060 mL	3.0150 mL
	40 mM	0.0904 mL	0.4522 mL	0.9045 mL	2.2612 mL
	50 mM	0.0724 mL	0.3618 mL	0.7236 mL	1.8090 mL
	60 mM	0.0603 mL	0.3015 mL	0.6030 mL	1.5075 mL
	80 mM	0.0452 mL	0.2261 mL	0.4522 mL	1.1306 mL
	100 mM	0.0362 mL	0.1809 mL	0.3618 mL	0.9045 mL