Valerianol
Valerianol is a sesquiterpene alcohol with anticancer, antibacterial, and antiviral activities. Valerianol selectively inhibits TPA (HY-18739)-induced Epstein-Barr virus early antigen (EBV-EA) activation (IC50=300 μM). Valerianol inhibits tumor promoter-mediated EBV-EA activation and also inhibits pathogenic bacteria such as Staphylococcus aureus.
For research use only. We do not sell to patients.
- CAS No.: 20489-45-6
- Formula: C15H26O
- Molecular Weight:222.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 20489-45-6
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Molecular Weight 222.37
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Formula C15H26O
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SMILES
OC(C)([C@@H]1CCC2=CCC[C@H]([C@@]2(C1)C)C)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)