E3 ligase Ligand 40
Based on 1 Customer Validation
E3 Ligase Ligand 40 is an E3 ligase ligand and can be used for the synthesis of PROTAC molecules.
For research use only. We do not sell to patients.
- Purity: 98.62%
- Formula: C13H15FN6O
- Molecular Weight:290.30
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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VHL |
Chemical Information
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Appearance Solid
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Molecular Weight 290.30
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Formula C13H15FN6O
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Color Light yellow to yellow
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SMILES
O=C(C1=CC=C(N=C1F)NC)NC2=NN=C(N(C)C)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 10 mg/mL (34.45 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4447 mL | 17.2236 mL | 34.4471 mL | 86.1178 mL |
| 5 mM | 0.6889 mL | 3.4447 mL | 6.8894 mL | 17.2236 mL | |
| 10 mM | 0.3445 mL | 1.7224 mL | 3.4447 mL | 8.6118 mL | |
| 15 mM | 0.2296 mL | 1.1482 mL | 2.2965 mL | 5.7412 mL | |
| 20 mM | 0.1722 mL | 0.8612 mL | 1.7224 mL | 4.3059 mL | |
| 25 mM | 0.1378 mL | 0.6889 mL | 1.3779 mL | 3.4447 mL | |
| 30 mM | 0.1148 mL | 0.5741 mL | 1.1482 mL | 2.8706 mL |