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Cat. No.: HY-172375

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E3 Ligase Ligand-linker Conjugate 170

E3 Ligase Ligand-linker Conjugate 170 (Compound I) exhibits anti-proliferative activity in non-Hodgkin's lymphoma cell SU-DHL-4 with IC₅₀ < 0.2 μM. E3 Ligase Ligand-linker Conjugate 170 is the conjugate composed of an E3 ligase ligand and a linker that can be used for PROTAC synthesis.

For research use only. We do not sell to patients.

CAS No.: 2379572-21-9
Formula: C₂₈H₃₀FN₅O₅
Molecular Weight:535.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

E3 Ligase Ligand-linker Conjugate 170 Chemical Structure

CAS No.: 2379572-21-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

CAS No. 2379572-21-9
Molecular Weight 535.57
Formula C₂₈H₃₀FN₅O₅
SMILES

O=C1N(C2C(NC(CC2)=O)=O)C(C3=C(NCC4=CC=C(CN5CC(N6CCOCC6)C5)C=C4F)C=CC=C31)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Anton MSC, et al., Methods of treating non-hodgkin lymphoma using 2-(2,6-dioxopiperidin-3-yl)-4-((2-fluoro-4-((3-morpholinoazetidin-1-yl)methyl)benzyl)amino)isoindoline-1,3-dione. WO2020210418A1

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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E3 Ligase Ligand-linker Conjugate 170

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E3 Ligase Ligand-linker Conjugate 170

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

E3 Ligase Ligand-linker Conjugate 170 Related Classifications

HY-172375 Related Classifications

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Keywords

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