E3 Ligase Ligand-linker Conjugate 234
E3 Ligase Ligand-linker Conjugate 234 (Compound 84) is a conjugate of an E3 ligase ligand and a linker, which can be used to synthesize PROTACs such as XYD224 (HY-184210).
For research use only. We do not sell to patients.
- Formula: C29H42FN5O4
- Molecular Weight:543.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 543.67
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Formula C29H42FN5O4
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SMILES
O=C(CCC1NC2=CC=C(C(F)=C2)N3CC4(C3)CCN(CC4)CC5CCN(C(OC(C)(C)C)=O)CC5)NC1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)