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Cat. No.: HY-187349

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E3 Ligase Ligand-linker Conjugate 241

E3 Ligase Ligand-linker Conjugate 241 is an E3 ligase ligand-linker conjugate that serves as a component of PROTAC, such as PROTAC NAMPT Degrader-31 (HY-187347). E3 Ligase Ligand-linker Conjugate 241 is applicable to research related to PROTAC synthesis.

For research use only. We do not sell to patients.

Formula: C₃₆H₄₈N₆O₈
Molecular Weight:692.80

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

E3 Ligase Ligand-linker Conjugate 241 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

All E3 Ligase Ligand-Linker Conjugates Isoforms :

In Vitro

E3 Ligase Ligand-linker Conjugate 241 serves as the E3 ligase ligand-linker conjugate moiety of PROTAC NAMPT Degrader-31 (HY-187347)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 692.80
Formula C₃₆H₄₈N₆O₈
SMILES

O=C1CCC(C(N1)=O)N2C(C3=CC=C(C=C3C2=O)N4CCC(CC4)N5CCN(CC5)C(C6CCN(CC6)C(CCC(OC(C)(C)C)=O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Song Y, et al. Discovery of a Potent NAMPT-Targeting PROTAC for the Suppression of Triple-Negative Breast Cancer via Macrophage Reprogramming. Journal of medicinal chemistry. 2026 Jul 23;69(14):16801-16818. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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E3 Ligase Ligand-linker Conjugate 241

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E3 Ligase Ligand-linker Conjugate 241

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Description

In Vitro

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

E3 Ligase Ligand-linker Conjugate 241 Related Classifications

HY-187349 Related Classifications

Bioz

Keywords

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