BMS 605339
BMS 605339 is a linear tetra-peptide α-ketoamide inhibitor of HCV NS3 protease. BMS 605339 can be used in research related to hepatitis C (HCV infection).
For research use only. We do not sell to patients.
- CAS No.: 630417-82-2
- Formula: C35H47N5O9S
- Molecular Weight:713.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
>100 μM
Compound: 35, BMS-605339
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Cytotoxicity against human HuH7 cells
Cytotoxicity against human HuH7 cells
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[PMID: 24555570] |
| Huh-7 | EC50 |
12 nM
Compound: 1; BMS-605339
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Antiviral activity against HCV genotype 1b Con1 expressing NS3 protease infected in human Huh7.5 cells assessed as reduction in viral RNA replication by luciferase reporter gene assay
Antiviral activity against HCV genotype 1b Con1 expressing NS3 protease infected in human Huh7.5 cells assessed as reduction in viral RNA replication by luciferase reporter gene assay
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[PMID: 27564532] |
Chemical Information
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CAS No. 630417-82-2
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Molecular Weight 713.84
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Formula C35H47N5O9S
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SMILES
O=C([C@H]1N(C[C@H](OC2=NC=CC3=C2C=CC(OC)=C3)C1)C([C@H](C(C)(C)C)NC(OC(C)(C)C)=O)=O)N[C@]4([C@H](C=C)C4)C(NS(=O)(C5CC5)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BMS 605339 Related Classifications
HY-106352 Related Classifications
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