Biotin-PEG4-SH
Based on 1 Customer Validation
Biotin-PEG4-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 95.0%
- No. CAS: 2762393-22-4
- Fòrmula: C20H37N3O6S2
- Peso molecular:479.65
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Almacenamiento:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Ver todos los productos específicos de isoformas PROTAC Linkers
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Actividad biológica
Descripciòn
IC50 & Target
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PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2762393-22-4
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Appearance Oil
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Peso molecular 479.65
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Fòrmula C20H37N3O6S2
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Color Off-white to light yellow
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SMILES
O=C(NCCOCCOCCOCCOCCS)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (208.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : 50 mg/mL (104.24 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMSO | 1 mM | 2.0849 mL | 10.4243 mL | 20.8485 mL | 52.1213 mL |
| 5 mM | 0.4170 mL | 2.0849 mL | 4.1697 mL | 10.4243 mL | |
| 10 mM | 0.2085 mL | 1.0424 mL | 2.0849 mL | 5.2121 mL | |
| 15 mM | 0.1390 mL | 0.6950 mL | 1.3899 mL | 3.4748 mL | |
| 20 mM | 0.1042 mL | 0.5212 mL | 1.0424 mL | 2.6061 mL | |
| 25 mM | 0.0834 mL | 0.4170 mL | 0.8339 mL | 2.0849 mL | |
| 30 mM | 0.0695 mL | 0.3475 mL | 0.6950 mL | 1.7374 mL | |
| 40 mM | 0.0521 mL | 0.2606 mL | 0.5212 mL | 1.3030 mL | |
| 50 mM | 0.0417 mL | 0.2085 mL | 0.4170 mL | 1.0424 mL | |
| 60 mM | 0.0347 mL | 0.1737 mL | 0.3475 mL | 0.8687 mL | |
| 80 mM | 0.0261 mL | 0.1303 mL | 0.2606 mL | 0.6515 mL | |
| 100 mM | 0.0208 mL | 0.1042 mL | 0.2085 mL | 0.5212 mL |
Biotin-PEG4-SH Related Classifications
HY-134704 Related Classifications
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