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Cat. No.: HY-106444A

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Fipamezole hydrochloride

Name: Fipamezole hydrochloride
Brand: MedChemExpress
SKU: HY-106444A
Availability: PreOrder

(Synonyms: MPV-1730 hydrochloride; JP-1730 hydrochloride)

Fipamezole hydrochloride is a potent and orally active α2-adrenergic receptor antagonist with K_i values of 9.2 nM, 17 nM, and 55 nM for human α2A, α2B, and α2C, receptors, respectively. Fipamezole hydrochloride is an anti-dyskinetic agent, and can be used for the study of Parkinson's disease.

For research use only. We do not sell to patients.

CAS No.: 150586-72-4
Formula: C₁₄H₁₆ClFN₂
Molecular Weight:266.74

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Fipamezole hydrochloride Chemical Structure

CAS No.: 150586-72-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 150586-72-4
Molecular Weight 266.74
Formula C₁₄H₁₆ClFN₂
SMILES

FC1=CC2=C(CC(C3=CN=CN3)(CC)C2)C=C1.Cl
Synonyms

MPV-1730 hydrochloride; JP-1730 hydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Juha-Matti Savola, et al. Fipamezole (JP-1730) is a potent alpha2 adrenergic receptor antagonist that reduces levodopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease. Mov Disord. 2003 Aug;18(8):872-83. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Chemical Information
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References

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Fipamezole hydrochloride

All Adrenergic Receptor Isoforms