Fmoc-N-(2-Boc-aminoethyl)-Gly-OH

Name: Fmoc-N-(2-Boc-aminoethyl)-Gly-OH
Brand: MedChemExpress
SKU: HY-W101718
Rating: 4.5 (0 reviews)

Cat. No.: HY-W101718 Purity: 99.76%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Fmoc-N-(2-Boc-aminoethyl)-Gly-OH is a Fmoc-protected glycine derivative that can be used in antibody agent coupling (ADC) synthesis. ADC consists of antibodies that are linked to ADC cytotoxins via ADC junctions.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Fmoc-N-(2-Boc-aminoethyl)-Gly-OH 화학구조

CAS No. : 141743-15-9

사이즈	재고	수량
무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
100 mg	해외재고보유	Estimated Time of Arrival: December 31
250 mg	해외재고보유	Estimated Time of Arrival: December 31
500 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	해외재고보유	Estimated Time of Arrival: December 31
5 g	견적 받기
10 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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•Related Small Molecules:

•Related Proteins:

View All ADC Linker Isoform Specific Products:

View All Isoforms

Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

Biological Activity
순도&문서
References
고객리뷰

제품 설명

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

440.49

화학식

C₂₄H₂₈N₂O₆

CAS No.

141743-15-9

Appearance

Solid

Color

White to off-white

SMILES

CC(C)(OC(NCCN(C(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)CC(O)=O)=O)C

선적

Room temperature in continental US; may vary elsewhere.

보관

RT, sealed storage, away from moisture and light

In solvent	-80°C	1 year
	-20°C	6 months

용액&용해도

In Vitro:

DMSO : 116.67 mg/mL (264.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2702 mL	11.3510 mL	22.7020 mL
5 mM	0.4540 mL	2.2702 mL	4.5404 mL
10 mM	0.2270 mL	1.1351 mL	2.2702 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.76%

Select Batch:

Data Sheet (271 KB) SDS (458 KB)

COA (250 KB) HNMR (294 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. Hiroyuki Naito, et al. (anti-her2 antibody)-drug conjugate. EP3130608

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2702 mL	11.3510 mL	22.7020 mL	56.7550 mL
	5 mM	0.4540 mL	2.2702 mL	4.5404 mL	11.3510 mL
	10 mM	0.2270 mL	1.1351 mL	2.2702 mL	5.6755 mL
	15 mM	0.1513 mL	0.7567 mL	1.5135 mL	3.7837 mL
	20 mM	0.1135 mL	0.5675 mL	1.1351 mL	2.8377 mL
	25 mM	0.0908 mL	0.4540 mL	0.9081 mL	2.2702 mL
	30 mM	0.0757 mL	0.3784 mL	0.7567 mL	1.8918 mL
	40 mM	0.0568 mL	0.2838 mL	0.5675 mL	1.4189 mL
	50 mM	0.0454 mL	0.2270 mL	0.4540 mL	1.1351 mL
	60 mM	0.0378 mL	0.1892 mL	0.3784 mL	0.9459 mL
	80 mM	0.0284 mL	0.1419 mL	0.2838 mL	0.7094 mL
	100 mM	0.0227 mL	0.1135 mL	0.2270 mL	0.5675 mL