Fmoc-NH-PEG12-CH2CH2COOH
Based on 1 Customer Validation
Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.96%
- CAS No.: 1952360-91-6
- Formula: C42H65NO16
- Molecular Weight:839.97
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1952360-91-6
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Appearance Liquid (Density: 1.175±0.06 g/cm3)
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Molecular Weight 839.97
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Formula C42H65NO16
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Color Light yellow to light brown
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SMILES
O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (119.05 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1905 mL | 5.9526 mL | 11.9052 mL | 29.7630 mL |
| 5 mM | 0.2381 mL | 1.1905 mL | 2.3810 mL | 5.9526 mL | |
| 10 mM | 0.1191 mL | 0.5953 mL | 1.1905 mL | 2.9763 mL | |
| 15 mM | 0.0794 mL | 0.3968 mL | 0.7937 mL | 1.9842 mL | |
| 20 mM | 0.0595 mL | 0.2976 mL | 0.5953 mL | 1.4881 mL | |
| 25 mM | 0.0476 mL | 0.2381 mL | 0.4762 mL | 1.1905 mL | |
| 30 mM | 0.0397 mL | 0.1984 mL | 0.3968 mL | 0.9921 mL | |
| 40 mM | 0.0298 mL | 0.1488 mL | 0.2976 mL | 0.7441 mL | |
| 50 mM | 0.0238 mL | 0.1191 mL | 0.2381 mL | 0.5953 mL | |
| 60 mM | 0.0198 mL | 0.0992 mL | 0.1984 mL | 0.4960 mL | |
| 80 mM | 0.0149 mL | 0.0744 mL | 0.1488 mL | 0.3720 mL | |
| 100 mM | 0.0119 mL | 0.0595 mL | 0.1191 mL | 0.2976 mL |
Fmoc-NH-PEG12-CH2CH2COOH Related Classifications
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