A-1155905
A-1155905 is a MCL-1 inhibitor (IC50=33.5 nM; Ki=0.58 nM) with anticancer activity. A-1155905 selectively binds to MCL-1 with sufficient affinity to disrupt the MCL-1-bim complex in living cells. A-1155905-induced death of MCL-1-dependent cell lines is caspase-dependent and occurs via apoptosis.
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- No. CAS: 2228052-37-5
- Fòrmula: C46H51FN6O6
- Peso molecular:802.93
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 2228052-37-5
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Peso molecular 802.93
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Fòrmula C46H51FN6O6
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SMILES
O=C(C)N(CC1)CCN1C2=CC=C(OCC3=C(C4=C(N(CCN5CCOCC5)C(C(O)=O)=C6CCCOC7=C(C=CC=C8F)C8=CC=C7)C6=CC=C4)C(C)=NN3C)C=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A-1155905 Related Classifications
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