AZ11657312
AZ11657312 is a P2X7 receptor antagonist with activity to restore stress natriuresis. AZ11657312 significantly increased renal medullary perfusion, only in mice treated with angiotensin II. AZ11657312 improves tissue oxygenation by blocking P2X7R, especially in areas of the kidney that are underoxygenated. Administration of AZ11657312 increased sodium excretion up to sixfold while normalizing blood pressure.
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- No. CAS: 804561-22-6
- Fòrmula: C26H35N3O3
- Peso molecular:437.57
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 804561-22-6
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Peso molecular 437.57
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Fòrmula C26H35N3O3
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SMILES
O=C(CC12CC3CC(CC(C2)C3)C1)NC4=CC(C(N5CC6OC(C5)CNC6)=O)=CC=C4C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)