DMPE-PEG2000-Mal
DMPE-PEG2000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
Para uso exclusivo en investigación. No vendemos a pacientes.
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
-
Help & FAQs
Actividad biológica
The structure of DMPE-PEG-Mal comprises three key components that work synergistically:
DMPE: Acts as a hydrophobic anchor, securely embedding the entire molecule into the membrane structure of lipid nanoparticles.
PEG chains: Act as hydrophilic spacers, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
Maleimide: A reaction interface located at the end of the PEG chain, it can undergo a specific Michael addition reaction with biomolecules containing thiol groups (-SH), such as peptides, antibodies, and aptamers, achieving targeting or tracking functions.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
SMILES
CCCCCCCCCCCCCC(OC[C@@H](OC(CCCCCCCCCCCCC)=O)COP(OCCNC(OCCNC(CCN1C(C=CC1=O)=O)=O)=O)(O)=O)=O.[n]
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz