PD 136450
PD 136450 (CAM 1189) is an antagonist for cholecystokinin 2 (CCK2). PD 136450 exhibits anti-secretory, anxiolytic and anti-ulcer activities, inhibits gastric acid secretion (IC50=1 mg/kg), and ameliorates the haemorrhagic lesions (IC50=4.7 mg/kg) in rats.
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- No. CAS: 139067-52-0
- Fòrmula: C35H40N4O6
- Peso molecular:612.72
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 139067-52-0
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Peso molecular 612.72
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Fòrmula C35H40N4O6
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SMILES
O=C(/C=C/C(N[C@@H](CNC([C@@](C)(CC1=CNC2=C1C=CC=C2)NC(OC3C4CC(CC3C5)CC5C4)=O)=O)C6=CC=CC=C6)=O)O
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Synonyms
CAM 1189
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PD 136450 Related Classifications
HY-120381 Related Classifications
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