2. Gene
  3. TP53 - tumor protein p53 Gene

TP53 - tumor protein p53 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca fascicularis

Also known as p53

Gene ID: 102135998 | Gene type: protein coding

About TP53

Primary_assembly 16: 7,637,058-7,660,843 reverse strand.Macaca_fascicularis_6.0:CM021954.1

This gene has 5 transcripts (splice variants), 253 orthologues and 2 paralogues.

TP53 Products(3)

mRNA Protein Name
XM_005582787.3 XP_005582844.1 cellular tumor antigen p53 isoform X2
XM_045375423.1 XP_045231358.1 cellular tumor antigen p53 isoform X1
XM_045375424.1 XP_045231359.1 cellular tumor antigen p53 isoform X2

TP53 Protein Structure

P53_TAD

P53_TAD: pfam08563 (5 - 29)

TAD2

TAD2: cl39845 (34 - 58)

P53

P53: cd08367 (108 - 288)

P53_tetramer

P53_tetramer: pfam07710 (318 - 357)

  • 0
  • 100
  • 200
  • 300
  • 393 a.a.
Protein Preferred Names Protein Names

cellular tumor antigen p53

Cellular tumor antigen p53

Tumor suppressor p53

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-A0169A Methyl aminolevulinate hydrochloride Activator 98.98% Unkown
HY-A0169 Methyl aminolevulinate / Unkown
HY-A0169AR Methyl aminolevulinate hydrochloride (Standard) Activator / Unkown
Clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Phase
HY-19980 Eprenetapopt 99.52% Phase 3
HY-19980G Eprenetapopt (GMP) / Phase 3
HY-156633 Rezatapopt p53 Activator 99.78% Phase 2
HY-16271 Kevetrin hydrochloride 98.0% Phase 2
HY-171499 Cenersen Inhibitor 95.07% Phase 2
HY-16270 Kevetrin / Phase 2
HY-176083 ASTX295 99.81% Phase 1
HY-124036 DS-7423 Inhibitor 99.83% Phase 1
Pre-clinical Phase
Bioactive Molecules (43)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10029 Nutlin-3a 99.13% Unkown
HY-P10925 Zolucatetide Inhibitor 99.31% Unkown
HY-P4210 Sulanemadlin Inhibitor 99.49% Unkown
HY-P1925A GO-203 TFA 98.39% Unkown
HY-15898 Y-320 99.03% Unkown
HY-158039 YCH2823 99.87% Unkown
HY-19980A PRIMA-1 98.0% Unkown
HY-148409 MMRi62 99.59% Unkown
HY-D0892 NSP-DMAE-NHS 99.48% Unkown
HY-114231 Exaluren 98.0% Unkown
HY-W181530 NCT02 98.14% Unkown
HY-17493 MI-773 96.29% Unkown
HY-107835 Flumethrin 99.29% Unkown
HY-179560 PMV6-PEG4-BI2536 Inhibitor 98.47% Unkown
HY-RS14912 TP53 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N1022 11-Hydroxytephrosin Inhibitor ≥98.0% Unkown
HY-RS14922 TP53RK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-100765 BI-0252 / Unkown
HY-107835R Flumethrin (Standard) / Unkown
HY-150620 BI-0282 Inhibitor / Unkown
HY-164828 Rezatapopt analog-1 / Unkown
HY-17493A MI-773 TFA 98.91% Unkown
HY-175000 L14-8 / Unkown
HY-178224 Morindone / Unkown
HY-180331 NVP-CFC218 Inhibitor / Unkown
HY-183547 WEE1/PKMYT1-IN-4 Inhibitor / Unkown
HY-186013 CML-07-119 Inducer / Unkown
HY-P11089 TP53 neoepitope Substrate / Unkown
HY-RS14913 Tp53 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14914 TP53AIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14915 TP53BP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14916 TP53BP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14917 TP53I11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14918 TP53I13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14919 TP53I3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14920 TP53INP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14921 TP53INP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15102 Trp53 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-10029A (Rac)-Nutlin-3 98.18% Unkown
HY-164544 USP7-055 Inhibitor / Unkown
HY-174511 Human TP53 mRNA / Unkown
HY-RS26028 Tp53i3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28596 Tp53inp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens TP53 NCBI NCBI:7157
Rattus norvegicus TP53 NCBI NCBI:24842
Macaca mulatta TP53 NCBI NCBI:716170