TP53 - tumor protein p53 Gene
Also Known as p53
Species: Macaca fascicularis
Gene Type: protein coding
Gene ID: 102135998
About TP53
Primary_assembly 16: 7,637,058-7,660,843 reverse strand.Macaca_fascicularis_6.0:CM021954.1
This gene has 5 transcripts (splice variants), 253 orthologues and 2 paralogues.
TP53 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| XM_005582787.3 | XP_005582844.1 | cellular tumor antigen p53 isoform X2 |
| XM_045375423.1 | XP_045231358.1 | cellular tumor antigen p53 isoform X1 |
| XM_045375424.1 | XP_045231359.1 | cellular tumor antigen p53 isoform X2 |
TP53 Protein Structure
P53_TAD
P53_TAD: pfam08563 (5 - 29)
TAD2
TAD2: cl39845 (34 - 58)
P53
P53: cd08367 (108 - 288)
P53_tetramer
P53_tetramer: pfam07710 (318 - 357)
- 0
- 100
- 200
- 300
- 393 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
cellular tumor antigen p53 |
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
Bioactive Molecules
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-A0169A | Methyl aminolevulinate hydrochloride | Activator | 98.98% | Unkown |
| HY-A0169 | Methyl aminolevulinate | / | Unkown | |
| HY-A0169AR | Methyl aminolevulinate hydrochloride (Standard) | Activator | / | Unkown |
Clinical Phase
Bioactive Molecules
(9)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-15676 | Idasanutlin | 99.93% | Phase 3 | |
| HY-19980 | Eprenetapopt | 99.52% | Phase 3 | |
| HY-19980G | Eprenetapopt (GMP) | / | Phase 3 | |
| HY-156633 | Rezatapopt | p53 Activator | 99.78% | Phase 2 |
| HY-16271 | Kevetrin hydrochloride | 98.0% | Phase 2 | |
| HY-171499 | Cenersen | Inhibitor | 95.07% | Phase 2 |
| HY-16270 | Kevetrin | / | Phase 2 | |
| HY-176083 | ASTX295 | 99.81% | Phase 1 | |
| HY-124036 | DS-7423 | Inhibitor | 99.83% | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(48)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-10029 | Nutlin-3a | 99.13% | Unkown | |
| HY-P10925 | Zolucatetide | Inhibitor | 99.31% | Unkown |
| HY-P4210 | Sulanemadlin | Inhibitor | 99.49% | Unkown |
| HY-P1925A | GO-203 TFA | 98.39% | Unkown | |
| HY-15898 | Y-320 | 99.03% | Unkown | |
| HY-19980A | PRIMA-1 | 98.0% | Unkown | |
| HY-158039 | YCH2823 | 99.87% | Unkown | |
| HY-148409 | MMRi62 | 99.59% | Unkown | |
| HY-114231 | Exaluren | 98.0% | Unkown | |
| HY-D0892 | NSP-DMAE-NHS | 99.48% | Unkown | |
| HY-W181530 | NCT02 | 98.14% | Unkown | |
| HY-17493 | MI-773 | 96.29% | Unkown | |
| HY-107835 | Flumethrin | 99.29% | Unkown | |
| HY-179560 | PMV6-PEG4-BI2536 | Inhibitor | 98.47% | Unkown |
| HY-RS14912 | TP53 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-N1022 | 11-Hydroxytephrosin | Inhibitor | ≥98.0% | Unkown |
| HY-RS14915 | TP53BP1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14922 | TP53RK Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-10029A | (Rac)-Nutlin-3 | 98.18% | Unkown | |
| HY-100765 | BI-0252 | / | Unkown | |
| HY-107835R | Flumethrin (Standard) | / | Unkown | |
| HY-107835S | Flumethrin-d5 | / | Unkown | |
| HY-150620 | BI-0282 | Inhibitor | / | Unkown |
| HY-164828 | Rezatapopt analog-1 | / | Unkown | |
| HY-17493A | MI-773 TFA | 98.91% | Unkown | |
| HY-175000 | L14-8 | / | Unkown | |
| HY-178224 | Morindone | / | Unkown | |
| HY-180331 | NVP-CFC218 | Inhibitor | / | Unkown |
| HY-180371 | NF-115 | Inducer | / | Unkown |
| HY-183547 | WEE1/PKMYT1-IN-4 | Inhibitor | / | Unkown |
| HY-184116 | A2AR/EGFR-IN-1 | / | Unkown | |
| HY-184244 | CAS-010 | Inhibitor | / | Unkown |
| HY-186013 | CML-07-119 | Inducer | / | Unkown |
| HY-P11089 | TP53 neoepitope | Substrate | / | Unkown |
| HY-RS14913 | Tp53 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14914 | TP53AIP1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14916 | TP53BP2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14917 | TP53I11 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14918 | TP53I13 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14919 | TP53I3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14920 | TP53INP1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14921 | TP53INP2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS15102 | Trp53 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-164544 | USP7-055 | Inhibitor | / | Unkown |
| HY-174511 | Human TP53 mRNA | / | Unkown | |
| HY-183877 | YO-2 | / | Unkown | |
| HY-RS26028 | Tp53i3 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS28596 | Tp53inp1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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