Pcca - propionyl-Coenzyme A carboxylase, alpha polypeptide Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 110821

Summary

Enables propionyl-CoA carboxylase activity. Predicted to act upstream of or within lipid catabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; nervous system; orbito-sphenoid; sensory organ; and urinary system. Used to study propionic acidemia. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and propionic acidemia. Orthologous to human PCCA (propionyl-CoA carboxylase subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Pcca Products (1)

mRNA Protein Name
NM_144844.2 NP_659093.2 propionyl-CoA carboxylase alpha chain, mitochondrial precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables propionyl-CoA carboxylase activity IMP
IMP: Inferred from mutant phenotype
11461925 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

propionyl-CoA carboxylase alpha chain, mitochondrial

  • PCCase subunit alpha

  • propanoyl-CoA:carbon dioxide ligase subunit alpha

  • propionyl CoA-carboxylase alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100013A1 (1R,2R)-2-PCCA hydrochloride 98.08% Unkown
HY-100013C 2-PCCA hydrochloride 99.61% Unkown
HY-100013 2-PCCA Agonist / Unkown
HY-100013B1 (1S,2S)-2-PCCA hydrochloride Control 99.65% Unkown
HY-RS10119 PCCA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21401 Pcca Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27920 Pcca Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pcca NCBI NCBI:5095