SLC2A14 - solute carrier family 2 member 14 Gene
Also Known as GLUT14; SLC2A3P3
Species: Homo sapiens
About SLC2A14
This gene has 21 transcripts (splice variants), 488 orthologues and 13 paralogues. Biased expression in testis (RPKM 31.0), bone marrow (RPKM 13.8) and 5 other tissues.
Summary
Members of the glucose transporter (GLUT) family, including SLC2A14, are highly conserved integral membrane proteins that transport hexoses such as glucose and fructose into all mammalian cells. GLUTs show tissue and cell-type specific expression (Wu and Freeze, 2002 [PubMed 12504846]).[supplied by OMIM, Mar 2008]
SLC2A14 Products (6)
| mRNA | Protein | Name |
|---|---|---|
| NM_001286233.2 | NP_001273162.1 | solute carrier family 2, facilitated glucose transporter member 14 isoform a |
| NM_001286234.2 | NP_001273163.1 | solute carrier family 2, facilitated glucose transporter member 14 isoform b |
| NM_001286235.2 | NP_001273164.1 | solute carrier family 2, facilitated glucose transporter member 14 isoform b |
| NM_001286236.2 | NP_001273165.1 | solute carrier family 2, facilitated glucose transporter member 14 isoform c |
| NM_001286237.2 | NP_001273166.1 | solute carrier family 2, facilitated glucose transporter member 14 isoform d |
| NM_153449.4 | NP_703150.1 | solute carrier family 2, facilitated glucose transporter member 14 isoform a |
| Molecular Function GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| enables D-glucose transmembrane transporter activity |
IDA
IDA: Inferred from direct assay
|
28971850 | GOA |
| enables dehydroascorbic acid transmembrane transporter activity |
IDA
IDA: Inferred from direct assay
|
28971850 | GOA |
| Biological Process GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| involved in D-glucose transmembrane transport |
IDA
IDA: Inferred from direct assay
|
28971850 | GOA |
| involved in dehydroascorbic acid transport |
IDA
IDA: Inferred from direct assay
|
28971850 | GOA |
| Cellular Component GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| located in plasma membrane |
IDA
IDA: Inferred from direct assay
|
27460888 | GOA |
SLC2A14 Protein Structure
Sugar_tr: Sugar (and other) transporter (39 - 489)
- 0
- 100
- 200
- 300
- 400
- 520 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
solute carrier family 2, facilitated glucose transporter member 14 |
|
SLC2A14 Antibodies
| Art. -Nr. | Produktname | Anwendung | Reactivity |
|---|---|---|---|
| HY-P83177 | Glucose Transporter GLUT3 Antibody (YA2922) | WB | Human, Mouse, Rat |
| HY-P83177A | Glucose Transporter GLUT3 Antibody (YA2922)(PBS only) | WB | Human, Mouse, Rat |
| HY-P84682 | SLC2A14 Antibody (YA4379) | IHC-P, ICC/IF, ELISA | Human |
| HY-P84682A | SLC2A14 Antibody (YA4379)(PBS only) | IHC-P, ICC/IF, ELISA | Human |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Hypoascorbemia |
|
|
| Micronodular Basal Cell Carcinoma |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | SLC2A14 | MGD | MGI:95757 |
| Others | SLC2A14 | NCBI |