Glucose Transporter GLUT3 Antibody (YA2922)
(Synonyms: SLC2A3; GLUT3; Solute carrier family 2; facilitated glucose transporter member 3; Glucose transporter type 3; brain; GLUT-3)Based on 1 Customer Validation
Glucose Transporter GLUT3 Antibody (YA2922) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Glucose Transporter GLUT3.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500-1:1000 |
Product Details
Glucose Transporter GLUT3 Antibody (YA2922) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Glucose Transporter GLUT3.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 54 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 54 kDa
Entrez Gene: 144195 Human ; 6515 Human ; 20527 Mouse ; 25551 Rat
SwissProt: P11169 Human ; Q8TDB8 Human ; P32037 Mouse ; Q07647 Rat
OMIM: 138170 Human
A synthetic peptide of human Glucose Transporter GLUT3
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Verification Images
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Western blot analysis of extracts from HepG2 (lane 2(20μg), RAW264.7 (lane 3(20μg) and C6 (lane 4(20μg) using Glucose Transporter GLUT3 (HY-P83177) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Background
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Function
Glucose Transporter GLUT3 is a Facilitative glucose transporter. Can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport. Required for mesendoderm differentiation[1][2][3].
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Subcellular Localization
Cell membrane; Multi-pass membrane protein; Perikaryon; Cell projection
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Expression
Tissue_specificity:Highly expressed in brain (PubMed:8457197) . Expressed in many tissues -
Subunit
Interacts with SMIM43; the interaction may promote SLC2A3-mediated glucose transport to meet the energy needs of mesendoderm differentiation
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SwissProt ID
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Synonyms
SLC2A3; GLUT3; Solute carrier family 2; facilitated glucose transporter member 3; Glucose transporter type 3; brain; GLUT-3
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Research Field
Signal Transduction
Documentation
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Data Sheet (232 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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User Guide for Antibodies (1077 KB)