Gapdhs - glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Gene
Also Known as Gapds; Gapd-s
Species: Mus musculus
Gene Type: protein coding
Gene ID: 14447
Summary
Enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Involved in flagellated sperm motility. Acts upstream of or within glycolytic process. Located in sperm fibrous sheath and sperm principal piece. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDHS (glyceraldehyde-3-phosphate dehydrogenase, spermatogenic). [provided by Alliance of Genome Resources, Apr 2022]
Gapdhs Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001290631.1 | NP_001277560.1 | glyceraldehyde-3-phosphate dehydrogenase, testis-specific isoform 1 |
| NM_008085.2 | NP_032111.1 | glyceraldehyde-3-phosphate dehydrogenase, testis-specific isoform 2 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
IDA
IDA: Inferred from direct assay
|
15546993 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in flagellated sperm motility |
IDA
IDA: Inferred from direct assay
|
15546993 | MGI |
| acts upstream of or within flagellated sperm motility |
IMP
IMP: Inferred from mutant phenotype
|
15546993 | MGI |
| acts upstream of or within glycolytic process |
IMP
IMP: Inferred from mutant phenotype
|
15546993 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cilium |
IDA
IDA: Inferred from direct assay
|
16687649 | MGI |
| located in motile cilium |
IDA
IDA: Inferred from direct assay
|
15546993 | MGI |
| located in sperm fibrous sheath |
IDA
IDA: Inferred from direct assay
|
16687649 | MGI |
| located in sperm principal piece |
IDA
IDA: Inferred from direct assay
|
9510974 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
glyceraldehyde-3-phosphate dehydrogenase, testis-specific |
|
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-B1087 | Prednisolone hemisuccinate | 99.89% | Unkown |
Clinical Phase
Bioactive Molecules
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-16361A | Omigapil maleate | Inhibitor | 99.84% | Phase 2 |
| HY-16361 | Omigapil | Inducer | / | Phase 2 |
| HY-147280 | Misetionamide | Inducer | 99.49% | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(101)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-D0849 | Sodium iodoacetate | Inhibitor | 99.91% | Unkown |
| HY-123962 | G6PD activator AG1 | 99.54% | Unkown | |
| HY-112758 | DLin-KC2-DMA | 99.88% | Unkown | |
| HY-120838 | Heptelidic acid | Inhibitor | 97.5% | Unkown |
| HY-157395 | malonyl-NAC | Inhibitor | 98.74% | Unkown |
| HY-43643 | DC-5163 | Inducer | 99.30% | Unkown |
| HY-N15156 | Thiotaurine | 99.27% | Unkown | |
| HY-156823 | GAPDH Positive Control siRNA (Human) | Pre-designed Set | 98.72% | Unkown |
| HY-156824 | GAPDH siRNA Positive Control (Mouse/Rat) | Pre-designed Set | 98.09% | Unkown |
| HY-171036 | GAPDH-IN-1 | Inhibitor | 98.10% | Unkown |
| HY-RS29497 | GAL3ST2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-132126 | SPHINX | Inhibitor | 99.87% | Unkown |
| HY-RS29457 | TMEM175 Monkey Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS00759 | ANXA11 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS00845 | APOC2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS05274 | GAPDHS Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-128788A | ddhCTP trisodium solution (100 mM) | Inhibitor | / | Unkown |
| HY-RS00844 | APOC1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS16258 | Lipt1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS16283 | FAM-labeled P3H3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29445 | Ndufaf6 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29463 | GCNT4 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29469 | GPR146 Domestic cattle Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29474 | Dpm3 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29475 | CEPT1 Human/Cat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29476 | Akap1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29477 | Mmachc Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29478 | Vps13b Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29483 | GM2A Cattle Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29484 | Tnxb Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29490 | Zpbp Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29491 | Taco1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29492 | Itpr1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29496 | Prkaa1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29498 | LOC771 Monkey Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29499 | SP1 Monkey Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29507 | Hnrnpdl Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29509 | Rab7a Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29510 | Ociad2 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29512 | AP1AR Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29515 | Slc30a8 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29516 | BLOC1S3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29518 | Rab7 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29519 | C1ra Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-119062 | A-800141 | Inhibitor | / | Unkown |
| HY-123668 | KM05382 | Inhibitor | / | Unkown |
| HY-128788 | ddhCTP | Inhibitor | / | Unkown |
| HY-131921 | DL-Glyceraldehyde 3-phosphate diethyl acetal barium | / | Unkown | |
| HY-161668 | Ru-Poma | / | Unkown | |
| HY-184150 | EN10 | Ligand | / | Unkown |
| HY-186183 | Normethyl-ZCAN262 | Modulator | / | Unkown |
| HY-N3247 | Monomethyl kolavate | Inhibitor | / | Unkown |
| HY-RS01637 | BRSK1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS01840 | CALM1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS01842 | CALM3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS02352 | CDK11A Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS03616 | DDIT4L Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS04221 | EHD1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS05787 | GRHL1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS05789 | GRHL3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS06491 | HUNK Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS10438 | PHKA2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS15382 | UBP1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29504 | Acot4 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-170714 | siRNA positive control (Rat GAPDH) (2-OMe) | Pre-designed Set | / | Unkown |
| HY-RS16268 | Islr Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS16274 | Human CDC27P10 Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS16289 | St6galnac4 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS16311 | Herc6 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS17563 | Anxa10 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS18382 | Cdk10 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS19408 | Apoa4 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS19983 | Apoa2 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS22883 | Trrap Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS23297 | Hipk2 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS23792 | Brsk2 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24288 | Trio Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24540 | Fosl2 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24560 | Anxa13 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24635 | Anxa6 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS25291 | Anxa4 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS25348 | Cnksr3 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS25659 | Anxa8 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS26152 | Calm2 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS26883 | Cdk15 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS27368 | Anxa9 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS27463 | Grhl2 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29448 | ILF2 Pig Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29449 | ANKRD31 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29456 | Ncr3lg1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29458 | Tmem19 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29459 | Tmem19 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29468 | Spaca1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29486 | SLC25A15 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29489 | Eqtn Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29493 | Efr3b Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29495 | Glis3 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29505 | Dnajc15 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29506 | ZNF22 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29508 | Myo19 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS29511 | Serpina1a Mouse Pre-designed siRNA Set A | / | Unkown |
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