2. Gene
  3. Gapdhs - glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Gene

Gapdhs - glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gapds; Gapd-s

Gene ID: 14447 | Gene type: protein coding

About Gapdhs

Summary

Enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Involved in flagellated sperm motility. Acts upstream of or within glycolytic process. Located in sperm fibrous sheath and sperm principal piece. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDHS (glyceraldehyde-3-phosphate dehydrogenase, spermatogenic). [provided by Alliance of Genome Resources, Apr 2022]

Gapdhs Products(2)

mRNA Protein Name
NM_001290631.1 NP_001277560.1 glyceraldehyde-3-phosphate dehydrogenase, testis-specific isoform 1
NM_008085.2 NP_032111.1 glyceraldehyde-3-phosphate dehydrogenase, testis-specific isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity IDA
IDA: Inferred from direct assay
15546993 MGI
Biological Process GO Annotation Evidence Reference Source
involved in flagellated sperm motility IDA
IDA: Inferred from direct assay
15546993 MGI
acts upstream of or within flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
15546993 MGI
acts upstream of or within glycolytic process IMP
IMP: Inferred from mutant phenotype
15546993 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cilium IDA
IDA: Inferred from direct assay
16687649 MGI
located in motile cilium IDA
IDA: Inferred from direct assay
15546993 MGI
located in sperm fibrous sheath IDA
IDA: Inferred from direct assay
16687649 MGI
located in sperm principal piece IDA
IDA: Inferred from direct assay
9510974 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glyceraldehyde-3-phosphate dehydrogenase, testis-specific

GAPDH-2

spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2

spermatogenic glyceraldehyde-3-phosphate dehydrogenase

Related Agents

Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-16361A Omigapil maleate Inhibitor 99.84% Phase 2
HY-16361 Omigapil Inducer / Phase 2
HY-147280 Misetionamide Inducer 99.49% Phase 1
Pre-clinical Phase
Bioactive Molecules (92)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-D0849 Sodium iodoacetate Inhibitor 99.91% Unkown
HY-123962 G6PD activator AG1 99.54% Unkown
HY-112758 DLin-KC2-DMA 99.88% Unkown
HY-120838 Heptelidic acid Inhibitor 97.5% Unkown
HY-157395 malonyl-NAC Inhibitor 98.74% Unkown
HY-N15156 Thiotaurine 99.27% Unkown
HY-156823 GAPDH Positive Control siRNA (Human) Pre-designed Set 98.72% Unkown
HY-43643 DC-5163 Inducer 99.30% Unkown
HY-156824 GAPDH siRNA Positive Control (Mouse/Rat) Pre-designed Set 98.09% Unkown
HY-171036 GAPDH-IN-1 Inhibitor 98.1% Unkown
HY-RS29497 GAL3ST2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-132126 SPHINX Inhibitor 99.87% Unkown
HY-RS29457 TMEM175 Monkey Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00759 ANXA11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00845 APOC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05274 GAPDHS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-128788A ddhCTP trisodium solution (100 mM) Inhibitor / Unkown
HY-RS00844 APOC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16258 Lipt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16283 FAM-labeled P3H3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29445 Ndufaf6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29463 GCNT4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29469 GPR146 Domestic cattle Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29474 Dpm3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29475 CEPT1 Human/Cat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29476 Akap1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29477 Mmachc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29478 Vps13b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29483 GM2A Cattle Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29484 Tnxb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29490 Zpbp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29491 Taco1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29492 Itpr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29498 LOC771 Monkey Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29499 SP1 Monkey Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29507 Hnrnpdl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-119062 A-800141 Inhibitor / Unkown
HY-123668 KM05382 Inhibitor / Unkown
HY-128788 ddhCTP Inhibitor / Unkown
HY-131921 DL-Glyceraldehyde 3-phosphate diethyl acetal barium / Unkown
HY-161668 Ru-Poma / Unkown
HY-186183 Normethyl-ZCAN262 Modulator / Unkown
HY-N3247 Monomethyl kolavate Inhibitor / Unkown
HY-RS01637 BRSK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01840 CALM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01842 CALM3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02352 CDK11A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03616 DDIT4L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04221 EHD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05787 GRHL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05789 GRHL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06491 HUNK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10438 PHKA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15382 UBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29504 Acot4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-170714 siRNA positive control (Rat GAPDH) (2-OMe) Pre-designed Set / Unkown
HY-RS16268 Islr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16274 Human CDC27P10 Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16289 St6galnac4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16311 Herc6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17563 Anxa10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18382 Cdk10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19408 Apoa4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19983 Apoa2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22883 Trrap Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23297 Hipk2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23792 Brsk2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24288 Trio Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24540 Fosl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24560 Anxa13 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24635 Anxa6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25291 Anxa4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25348 Cnksr3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25659 Anxa8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26152 Calm2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26883 Cdk15 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27368 Anxa9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27463 Grhl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29448 ILF2 Pig Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29449 ANKRD31 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29456 Ncr3lg1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29458 Tmem19 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29459 Tmem19 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29468 Spaca1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29486 SLC25A15 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29489 Eqtn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29493 Efr3b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29495 Glis3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29496 Prkaa1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29505 Dnajc15 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29506 ZNF22 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29508 Myo19 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gapdhs NCBI NCBI:26330