PIANP - PILR alpha associated neural protein Gene

Also Known as PANP; LEDA1; leda-1; C12orf53

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 196500

About PIANP

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:6,692,178-6,700,815 (from NCBI)

This gene has 6 transcripts (splice variants) and 117 orthologues. Biased expression in brain (RPKM 10.4), endometrium (RPKM 2.8) and 3 other tissues.

Summary

This gene encodes a ligand for the paired immunoglobin-like type 2 receptor alpha, and so may be involved in immune regulation. Alternate splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Sep 2011]

PIANP Products (3)

mRNA Protein Name
NM_001244014.2 NP_001230943.1 PILR alpha-associated neural protein isoform b precursor
NM_001244015.2 NP_001230944.1 PILR alpha-associated neural protein isoform a precursor
NM_153685.4 NP_710152.1 PILR alpha-associated neural protein isoform a precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PIANP Protein Structure

AJAP1_PANP_C

AJAP1_PANP_C: AJAP1/PANP C-terminus (106 - 276)

  • 0
  • 100
  • 200
  • 282 a.a.
Protein Preferred Names Protein Names

PILR alpha-associated neural protein

  • PILR-associating neural protein

PIANP Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PIANP Q8IYJ0 DEFB127 Homo sapiens Q9H1M4
Validated Y2H
32296183
Intra
PIANP Q8IYJ0 CMTM7 Homo sapiens Q96FZ5
Validated Y2H
32296183
Intra
PIANP Q8IYJ0 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
Intra
PIANP Q8IYJ0 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
Intra
PIANP Q8IYJ0 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant PIANP Proteins

Cat. No. Product Name Accession Purity
HY-P77461 PANP/C12orf53 Protein, Human (HEK293, Fc) Q8IYJ0-1 (S32-P178) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10472 PIANP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21020 Pianp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27537 Pianp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PIANP VGNC VGNC:64158
Canis familiaris PIANP VGNC VGNC:44518
Mus musculus PIANP MGD MGI:2441908
Bos taurus PIANP VGNC VGNC:32855
Rattus norvegicus PIANP RGD RGD:1304952
Others PIANP NCBI